无创通气在COPD合并Ⅱ型呼吸衰竭中的临床价值探讨

Approach to the Clinical Value of Noninvasive Ventilation on COPD Combined with Type Ⅱ Respiratory Failure

目的探讨双水平正压通气(BiPAP)在慢性阻塞性肺疾病(COPD)合并Ⅱ型呼吸衰竭中的临床价值。方法74例COPD合并Ⅱ型呼吸衰竭患者随机分为治疗组和对照组各37例,两组均给予抗感染、应用糖皮质激素、支气管扩张剂和持续低流量氧疗等常规治疗,治疗组同时加用BiPAP呼吸机通气治疗,对照组给予双鼻导管吸氧治疗。结果两组患者治疗后临床症状均有不同程度缓解,治疗组较对照组起效更快,疗效更好;血气分析均有显著改善,治疗组改善程度明显优于对照组,两组比较差异有统计学意义(P<0.05)。结论BiPAP无创通气治疗COPD合并Ⅱ型呼吸衰竭无创伤、疗效确切,能迅速纠正缺氧和二氧化碳潴留,改善临床症状,缩短住院治疗时间,值得临床广泛应用。

Objective Approach to the clinical value of bi-level positive airway pressure(BiPAP) ventilation on chronic obstructive pulmonary disease(COPD) combined with type Ⅱ respiratory failure. Methods 74 patients with COPD combined with type Ⅱ respiratory failure were randomLy and equally divided into study group(37) and control group(37),respectively. Both groups were given conventional therapy including anti-infection,glucocorticoid,bronchodilators,and continuous low flow oxygen therapy and so on. The study grou...