丹参酮ⅡA磺酸钠治疗冠心病心绞痛疗效观察

目的观察丹参酮ⅡA磺酸钠注射液对冠心病心肌缺血的有效性及对血脂、血液流变学的影响。方法将127例冠心病患者随机分为治疗组(65例)与对照组(62例),对照组常规应用硝酸异山梨酯与阿司匹林等,治疗组在常规治疗基础上加用丹参酮ⅡA磺酸钠注射液50mg(1次/d,疗程2周),每例于治疗开始前1d与结束后次日,进行血脂、血液流变学与心电图(ECG)检测。结果两组心肌缺血症状治疗前后均有改善,与对照组相比治疗组的效果更为显著(P<0.05),治疗组血脂、血液流变学所有指标均显著下降(P<0.05),其改变血脂、血液流变学指标的疗效优于对照组(P<0.05)。结论丹参酮ⅡA磺酸钠有降脂、改善血液流变学作用,是治疗冠心病心肌缺血的一种有效的药物。

Objective To observe the clinical curative effect of tanshinone ⅡA sulfonic acid natrium injection on myocardial ischemia and blood lipids,hemorreology in patients with coronary artery disease (CAD). Methods 127 cases of CAD were randomly divided into the treatment group(65 cases)and the control group(62 cases).The control group was treated with sorbitrate and aspirin. While the treatment group was treated with tanshinone ⅡA sulfonic acid natrium injection once a day for two weeks,based on the conventional ...