摘要
目的探讨紫杉醇(安泰素)联合铂类药物组成的TP方案和国产紫杉醇(紫素)联合铂类药物组成的PTP方案以及环磷酰胺加铂类药物和多柔比星组成的CAP方案治疗上皮性卵巢癌的疗效及毒性。方法对1997年7月及2004年12月采用TP、PTP及CAP化疗方案治疗的卵巢癌患者进行回顾性分析。TP组28例,PTP组22例,CAP组18例。结果TP组有效率为53.6%,PTP组有效率为54.5%,CAP有效率为44.4%。三组的一线用药有效率分别为83.3%,62.5%和50.0%;二线用药的有效率分别为31.2%,33.3%和25.0%。TP组和PTP组的一线和二线用药有效率均高于CAP方案(P<0.05)。结论TP和PTP作为一线和二线用药的疗效均优于CAP,TP与PTP在疗效及副作用上无明显差异。
Objective To study the effect and toxicities of paclitaxel combined with platinum(TP) and paclitaxel(Chinese) combined with platinum (PTP) in the treatment of epithelial ovarian cancer, and to compare with the combination of cyclophosphamide,adriamycin and platinum(CAP). Methods A retrospective analysis in the treatment of ovarian cancer with paclitaxel and CAP from 2000 to 2004 was done. Including 28 cases in TP, 22 cases in PTP and 18 cases in CAP group. Result The response rate (RR) in TP,PTP and CAP was...
出处
《肿瘤研究与临床》
CAS
2005年第S1期12-14,共3页
Cancer Research and Clinic
关键词
卵巢上皮癌
化疗
紫杉醇
Epithelial ovarian cancer
Paclitaxel
Chemotherapy
