华蟾素辅助治疗晚期消化系统肿瘤近期疗效观察

The Patients with Advanced Digestive System Carcinoma Treated with Injection Hua-chen-su

目的:总结中药抗癌针剂华蟾素辅助治疗晚期消化系统肿瘤的效果.方法:用华蟾素15～20mL加入生理盐水250mL静脉滴注,连续20d为1个疗程,一般连用1～3个疗程;同时配合中医辨症论治口服中药.其中10例同时接受了CF+5FU+L-OHP方案化疗,1例接受了CF+5FU方案化疗.结果:CR为0,PR为2,NC12例.PD12例,其中2例PR病例均接受了化疗;病人腹胀、肝区痛、食欲不振、神疲乏力等症状明显改善,肝功能明显改善,生活质量明显提高.结论:静脉滴注华蟾素应是目前治疗晚期消化系统肿瘤一项比较合适的辅助措施.

A total of 26 patients with advanced digestive system carcinoma treated with injection Huachansu .Among them,6 with gastric carcinoma,4 with colorectal carcinoma, 11 with primary liver carcinoma,and 5 with metastasic liver carcinoma. All patients were treated with injection Huachansu 15~20mL daily ,as 20 days a cycle. And all of them were treated with Traditional Chinese Medicine(TCM) concurrently. Results: Response evaluation was performed according to World Health Organization (WHO) recommendations. Of the 26 patients, none had complete response;2 had a partial response, whom were treated with chemotherapy concurrently;12 non-change and 12 progress disease. The symptoms such as anorexia, asthenia ,pain in liver ,abdominal distention were relieved significantly. And abnormal liver function had been ameliorated. The life-quality of patients had been promoted apparently.