铝佐剂在幽门螺杆菌疫苗中的应用

Application of aluminium adjuvant in the development of helicobacter pylori vaccine

铝佐剂是到目前为止唯一被批准用于人用疫苗的佐剂,长期普遍用于多种疫苗。最近,在幽门螺杆菌(Helico-bacter pylori,Hp)疫苗的研究中,有一些关于铝佐剂的报道。本文就铝佐剂的组成、制备、免疫机制及在抗幽门螺杆菌疫苗中的研究状况做一综述。

Aluminum compounds are the only licensed adjuvant used currently in the vaccines for human. There are some investigation reports about aluminium adjuvant using in the development of helicobacter pylori vaccines in recent years. The components, preparation, immu-nological mechanisms, and the research state in helicobacter pylori vaccines of aluminium adjuvant are summarized in this article.