New Cyclolignan Esters and Their Antidiabetic Activitity from the Root of Rhus semialata

Rhus semialata is one of five Rhus species (Anacardiaceae), distributed in the island of Taiwan. In the early days,the pericarp of R. semialata was commonly used as a substitute of salt by indigenous mountain people. The root of it is also a folk herb for treating diarrhea, spermatorrhea and malaria.[1,2] This paper describes the isolation and structural elucidation of new cyclolignan esters 3 and 4, and two known compounds: cyclolariciresinol (1) and lynoiresinol (2) isolated from the n-butanol extract of R. semialata.……