液质联用仪鉴别保健食品中伟哥及其在人体中的代谢产物

Identification for Sildenafil and Its Metabolins by HPLC - MS

在保健食品的分析中,针对保健功能分析一般分为功效成分分析和违禁添加药物分析二类.目前保健食品中的功效成分主要由合成化学品、天然提取物等构成,由于申报过程中除进行化学性一般评介外,还有功效的生物学评介.……

This paper introduces an analytical system to detect the prohibited drug in functional food- Sildenafil by HPLC - MS, from chromatographic filtration to validation by mass spectrum. Meanwhile it also does some researches on sildenafil' s metabolins by mass spectrum and draws some possible metabolin' s structure.