摘要
乌头生物碱各成分毒性差异很大,其中乌头碱的毒性为其它成分的100～2000倍,是引起中毒和死亡的主要原因.乌头生物碱种类多,在煎煮或泡制过程中易水解产生不同水解产物,进入体内后代谢情况又不明,因此采用液相色谱方法对体内检材乌头碱成分仅靠保留时间确定依据不足,定量工作更是无法开展.……
Aconitum alkaloids consist of a group of compounds. The toxicity of the compounds make a great difference. Aconitine is more deadly poisonous than the others. The quantity of aconitine is crucial for judging case. This article established an analysis method for aconitine in the human body with LC - MS instrument. The quantitative analysis method was applied in several cases and proved to be highly effective and precise.
出处
《分析测试学报》
CAS
CSCD
北大核心
2004年第z1期57-61,共2页
Journal of Instrumental Analysis
