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氯诺昔康及曲马多用于老年人胆囊切除术后自控镇痛的比较

Comparison of lornoxicam with tramadol for postoperative patient controlled analgesia in geriatric patients with chollecystectomy
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摘要 目的:对氯诺昔康在胆囊切除术后自控镇痛的有效性和安全性进行评价.方法:将60例行胆囊切除术后的老年患者随机分为两组,L组(氯诺昔康40~48mg+氟哌利多5mg)和T组(曲马多组500~600mg+氟哌利多5mg),观察术后4,8,12,24,32,48h的疼痛程度,镇静评分,恶心、呕吐、尿潴留等不良反应发生情况.结果:L组和T组在镇痛效果上无显著差别,但L组中恶心、呕吐等不良反应发生率明显低于T组.结论:氯诺昔康用于老年人胆囊切除术后自控镇痛效果确切,不需特别减量,不良反应少,在老年人胆囊切除术后自控镇痛中使用较为理想.
出处 《中国新药杂志》 CAS CSCD 北大核心 2004年第z1期11-13,共3页 Chinese Journal of New Drugs
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