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二异丙酚靶控输注在小儿全身麻醉中的应用研究 被引量:2

Study of general anesthesia with target-controlled infusion of propofol in children
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摘要 目的 评价二异丙酚靶控输注 (TCI)在小儿全身麻醉中的诱导和术后苏醒过程。方法4 0例因鼾症即儿童阻塞性睡眠呼吸暂停低通气综合征 (OSAHS)拟行手术治疗的患儿 ,随机分为常规静吸复合麻醉 (A)组及二异丙酚静脉靶控输注 (B)组 ,每组 2 0例。观察患儿麻醉诱导时血压和心率变化及气管插管的反应 ;记录术毕停麻醉药后患儿自主呼吸恢复时间、呼之睁眼时间、拔管时间和离开手术室时间 ;观察患儿拔管后即刻、离开手术室、拔管后 1h、3h和 2 4h的警觉 /镇静 (OAA/S)评分 ;观察术后恶心呕吐等副反应。结果 ①两组诱导时 ,血压、心率变化差异无显著性意义 ;插管反应发生率A组显著高于B组 ;②B组患儿术后自主呼吸恢复时间、呼之睁眼时间、拔管时间和离开手术室时间显著早于A组 ;③B组患儿在拔管后即刻、离开手术室、拔管后 1h、3h的OAA/S评分显著高于A组。两组术后恶心呕吐发生率无显著性差异。结论 与常规小儿静吸复合麻醉比较 ,二异丙酚TCI麻醉诱导更加平稳 ,术毕小儿苏醒质量更快更优良 ,为临床麻醉医生提供了较安全可靠的麻醉方法。 Objective To compare the effects of target-controlled infusion (TCI) of propofol and usual way on the safety and efficacy of general anesthesia in children.Methods Forty children with obstructive sleep apnea hyperpnoea syndrome, aged from 4.5 to 11 yr undergoing surgical treatment were randomly divided into two groups. In group A, anesthesia was induced with propofol 1.5 ~2?mg/kg, fentanyl 2?μg/kg and Atracurium 0.5 ?mg/kg and maintained with 1% propofol and 1%~2% isoflurane inhalation. In group...
出处 《中华小儿外科杂志》 CSCD 北大核心 2004年第6期62-64,共3页 Chinese Journal of Pediatric Surgery
关键词 二异丙酚 麻醉药 全身 麻醉 静脉内 Propofol Anesthetics general Anesthesia intravenous
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  • 1刘华程,上官王宁,连庆泉.小儿异丙酚药代动力学及其靶控输注[J].实用医学杂志,2005,21(4):437-438. 被引量:2
  • 2寿红艳,徐旭仲,金勉.短小手术患儿异丙酚靶控输注与氧化亚氮-异氟醚吸入麻醉效果的比较[J].中华麻醉学杂志,2005,25(6):473-474. 被引量:6
  • 3连庆泉,刘华程,上官王宁,徐旭仲,王增寿,吴一兵,姚尚龙.小儿异丙酚靶控输注系统准确性的评价[J].中华麻醉学杂志,2006,26(2):118-121. 被引量:17
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