新疆出血热的病理学观察及与临床联系的探讨

Investigation on Pathology of Xinjiang Hemorrhagic Fever and Its Relationship with Clinical Manifestation

本文报道对2例完整、4例不全的新疆出血热尸体解剖材料进行病理组织学的观察结果。结果表明新疆出血热的基本病理改变是全身毛细血管的功能性障碍、主要脏器的弥漫性血管内凝血,实质脏器可见到程度和范围不同的细胞变性和坏死,而炎性细胞浸润不显,肾脏的病变轻微。本文对该病病原、出血机制、病理与临床联系等问题进行了分析和讨论,认为本病在病理与临床表现等方面有别于肾病综合症出血热,符合无肾病综合症出血热,并提出在临床治疗上要过“五关”,观察病情要“五注意”的建议。

This paper reported the results of investigation on the pathology of Xinjiang hemorrhagic fever in two intact and four incomplete dead bodies of patients with this disease autopsied. The results indicated that the fundamental pathologic changes were the disfunction of generalized capillary, the disseminated intravascular coagulation of principle vescera, the degeneration and necrosis with different degrees and range of cells in parenchimatous organs while the filtration of inflammatory cells was not obvious...