不同光照制对雄性小鼠生殖影响的研究

Effects of abnormal light-dark regime on male reproduction in mice.

目的 探讨不同光照制对雄性小鼠生殖的影响。方法 取昆明种雄性小鼠作短期持续光照、持续黑暗、反相光照3种光照制处理。观察小鼠睾丸、附睾重量及光镜下睾丸、附睾组织学变化、精子数量、精子活动度、精子畸形率。结果 各组小鼠睾丸、附睾重量无显著性差异,而且各实验组光镜下睾丸、附睾组织学均未见异常。与对照组相比,黑暗小鼠和反相光照组小鼠精子数量明显降低,此外,反相光照组小鼠精子畸形率显著增加。结论 异常光照周期可能影响雄性小鼠生殖能力。

Objective: To evaluate the effect of abnormal light - dark regime on male reproduction in mice. Methods: Male mice were treated by continuous light , continuous dark and light - dark inversion for a short period. Testicular histology and weight, epididymal histology and weight,sperm amount,sperm motility and morphology were measured.Results:Testicular weight and epididymal weight both had no significant changes in all experimental groups compared with controls, and no histopathological abnormalities were ob...