脓胸患者测定C-反应蛋白、血沉及白细胞计数的临床意义

Clinical Significance of Determining Plasma Concentration D-dimer in Patients With Coronary Heart Disease.

目的:对脓胸患者治疗过程中进行C-反应蛋白(CRP)、红细胞沉降率(ESR)771白细胞总数(WBC)的监测,探讨其对治疗效果的评估,以便更好的指导临床治疗。方法:对28名临床确诊为脓胸的住院病人,于进行抗生素治疗的第1天起,连续检测病人的CRP、ESR和WBC,直至康复出院。结果:28名病人的CRP在抗生素治疗后出现持续的下降,与病情相符,至患者康复出院后,有10例CRP正常;而ESR于应用抗生素后继续上升,3 d～4 d后开始出现下降,至患者康复出院后,仅有3例正常;WBC总数大部分病人开始时增高,但有4例增高不明显,应用抗生素后,WBC总数出现明显的下降,至患者康复出院时,有25例在正常范围内或稍低。结论:作为急性时相反应蛋白之一的CRP水平增高要早于ESR和WBC总数,其下降曲线与治疗情况相符。所以CRP不仅可以作为临床诊断,而且可以应用于对临床病人的治疗指导。

Objective Plasma levels of D-dimer, a degradation product of cross-linked fibrin, were elevated in the presence of thrombus. This paper was to study the relationship between plasma concentration of D-dimer and clinical classification and severity in patients with coronary heart disease. Methods The concentrations of fibrin D-dimer from 70 patients (AMI 11cases, UA 27 cases and SA 22 cases) and 30 healthy adults plasmas-were determined with Liatest method. Results The level of plasma D-dimer in AMI and UA ...