大肠癌患者血浆脂蛋白(a)与CEA水平的观察与分析

Observation and Analysis of Plasma Lp(a) and CEA in Patients with Iarge Intestin

目的 :测定大肠癌患者血浆脂蛋白 (a)和血脂含量 ,探讨其水平变化的临床意义。方法 :采用单克隆抗体浊度法和酶联免疫吸附试验 (EL ISA)法测定了 5 6例大肠癌患者和 87例健康者的血浆脂蛋白 (a)和 CEA的含量。结果 :大肠癌患者的血浆脂蛋白 (a)和 CEA水平较健康对照组增高有非常显著差异 (P<0 .0 1) ,其灵敏度与特异性分别为 5 7.1%、6 2 .5 %和 97.9%、79.31%。结论 :血浆脂蛋白 (a)可能有助于大肠癌患者辅助诊断。

Objective To study changes and clinical significances of plasma Lp(a) and CEA in patients with intestinal cancer.Methods Monoclonal antibody turbidimetry and ELISA methods were used to detect the plasma Lp (a) and CEA in 56 patients with large intestinal cancer and 87 healthy persons.Results Plasma Lp(a) and CEA in patients with large intestinal cancer were higher than healthy persons (P<0.01).Its sensitivity and specificity were 57.1 %、62.5 % and 91.9 %、79.3 % respectively.Conclusions Plasma Lp (a) and ...