乙肝病毒携带母亲乳汁中乙肝病毒标志物与HBV-DNA的检测意义

Detection of Hepatitis B Virus Marker and HBV-DNA in the Parturients with Hepatitis B

目的 :探讨乙型肝炎产妇产后能否进行母乳喂养。方法 :选择住院分娩的乙型肝炎产妇 32 1例 (肝功能均正常 ) ,其中血清 HBs Ag、HBe Ab(+/ - )、HBc Ab阳性 2 10例为小三阳组 ,HBs Ag、HBe Ag、HBc Ab均阳性 111例为大三阳组。分别留取产后 3d～ 5 d的初乳进行乳汁乙肝病毒标志物 (HBV- M)检测。结果 :两组乳汁中 HBs Ag、HBe Ag、HBc Ab、HBV- DNA阳性率比较 ,差异有显著性意义 (P<0 .0 5 )。结论 :产妇初乳中 HBV- DNA阳性及产妇血清中大三阳者 (HBs Ag、HBe Ag、HBc Ab阳性 )不宜哺乳 ,初乳中单纯 HBs Ag阳性、而 HBV- DNA为阴性的产妇可以哺乳 ,但应给予正确的哺乳指导。

Objective To study the breast feeding of the parturients with hepatitis B after delivery.Methods 321 parturients with hepatitis B (liver function was normal) were selected and divided into two groups: single positive group(n=210) positive for serum HBsAg and double positive group(n=111) positive for both HBsAg and HBeAg.Hepatitis B virus marker (HBV-M) was detected in the colostrums 3 to 5 days after delivery.Results There was very significant difference in the positive rate of HBsAg, HBeAg, HbcAg and HBV-...