重型颅脑损伤脑灌注压及颈内静脉氧饱和度与预后的关系

Relationship between saturation Of jugular vein oxygen, cere-bral perfusion pressure, and prognosis of severe head injuries

目的 探讨重型颅脑损伤病人(GCS≤8分)脑灌注压(CPP)与颈内静脉氧饱和度(Sjvo2)与预后的关系。方法 对49例重型颅脑损伤患者行颈内静脉取血测得(Sjvo2),同时行脑室穿刺进行颅内监护。结果 ①Sjvo2、CPP与预后显著相关,Sjvo2≥75%或≤45%预后不良;CPP <60mmHg以下,预后良好率明显减低,死亡率明显增高, Sjvo2、CPP相结合可以互为补充。结论 Sjvo2与CPP监测相结合,能较可靠反映脑供血及脑氧代谢状况,对治疗具有重要指导意义。

Objective To determine the effects of saturation of jugular vein oxygen(Sjvo2) andcerebral perfusion pressure(CPP)on prognosis in patients with severe head injuries.Methods Sjvo2and CPP was tested in forty-nine patients with severe head injury who were divided into group on thebasis of their own CPP and Sjvo2,respectively.Results Both Sjvo2 and CPP were significantlycorrelated with prognosis.Sjvo2≥75% or≤45%,and CPP≤60mmHg were correlated with poor prognosis.Conclusion Monitoring of Sjvo2 and CPP is reliable to predict prognosis of severe head injuries,which is helpful to treatment.