氟罗沙星和环丙沙星治疗术后肺炎的临床对比观察

The Clinical Study of Fleroxacin and Cinrofloxacin in the Treatment of Postoperative Pneumonia

目的 比较氟罗沙星和环丙沙星治疗术后肺炎的疗效。方法 将40例术后肺炎患者随机分为两组,每组20例。氟罗沙星组以氟罗沙星(0.2～0.4g qd)静脉滴注,环丙沙星组施以环丙沙星(200ml bid)静脉滴注,疗程为5天。观察治疗后两组的临床疗效、痰培养中细菌清除率和患者转阴率。结果 与环丙沙星组相比,氟罗沙星组的治疗有效率、细菌清除率和患者转阴率明显提高(P<0.05)。结论 氟罗沙星在术后肺炎疗效明显优于环丙沙星。

Obejucive To discuss the therapeutic effects of Fleroxacin(FLRX) and Cinrofloxacin(CFLX) in the treatment of postoperative pneumonia. Mehtods Forty patients with postoperativepneumonia were randomly divided into 2 groups, FLRX group(n=20) were subjected to Fleroxacin(0.2～0.4givdrip qd), and CFLX group (n=20) were in modality of Cinrofloxacin(200ml ivdrip bid),both group weretreated for 5d. The therapeutic efficiency, the rates of bacterial cleaning and negative were analyzedafter therapy. Results Compare CFLX group, the therapeutic efficiency of FLRX group, and the ratesof bacterial cleaning and negative were significantly higher(P<0.05). Conclusions In the treatment ofpostoperative pneumonia, Fleroxacin is better than Cinrofloxacin.