肠易激综合征患者肛门直肠感觉阈值和动力学的改变

Sensation thresholds and dynamic study of the anorectum in patients with irritable bowel syndrome

采用 PC Polygraf HR高分辨多道胃肠功能测定仪 ,检测 42例肠易激综合征 ( IBS)患者的肛门直肠压力、直肠容量感知、疼痛阈值、耐受阈值等指标 ,并与 15例健康人做对照。结果发现 IBS的直肠静息压、肛管括约肌静息压、最大缩窄压及肛管长度与对照组无显著性差异 ( P>0 .0 5 ) ,而初始感觉阈值、疼痛阈值、排便阈值腹泻组低于正常对照组 ( P<0 .0 5 ) ,便秘组高于正常对照组 ( P<0 .0 5 )。排便时 IBS便秘组患者的肛管松弛压高于正常对照组 ( P<0 .0 5 )。提示

To study the dynamics features and sensation functions of the anorectum in patients with irritable bowel syndrome(IBS),multichannel and single balloon anorectal function detector of PC polygraf HR was applied in 42 patients with IBS as well as in 15 normal subjects to measure such parameters as anorectal pressure,rectal sensation volume thresholds,rectal defecation volume thresholds,and rectal maximum tolerable volume thresholds.The results showed that rectal resting pressure,anal resting pressure,anorectal sphincteric squeezing pressure and the length of high pressure zone were not different between the patients with IBS and the normal subjects(P>0.05).Rectal sensation volume thresholds,rectal defecation volume thresholds,rectal maximum tolerable volume thresholds were higher in constipation group of IBS than those in normal subjects(P<0.05),but were lower in diarrhea group of IBS than those in normal subjects(P<0.05).Relaxation pressure of sphincter during defecation was higher in constipation group of IBS than that in normal subjects(P<0.05).It is conclued that rectal sensation function to irritation and defcation function in patients with IBS was abnormal.