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脂质体作为玻璃体内注射药物载体的应用 被引量:2

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摘要 脂质体作为药物载体能明显提高玻璃体内注射药物的安全性和有效性。现主要应用于治疗眼内感染、预防增生性玻璃体视网膜病变以及基因转染的载体。
作者 贡亦清 陈逖
出处 《眼科》 CAS 2003年第6期364-367,共4页 Ophthalmology in China
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参考文献23

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同被引文献23

  • 1毕宏生,崔彦,张建华,王兴荣,解孝锋.5-氟尿嘧啶聚乳酸微球防治实验性增生性玻璃体视网膜病变的效果观察[J].中华眼科杂志,2006,42(1):37-41. 被引量:10
  • 2MARTINEZ-SANCHO C,HERRERO-VANRELL R,NEGRO S.Vitamin A palmitate and acyclovir biodegradable microspheres for intraocular sustained release[J].Int J Pharm,2006,326(1-2):100-106.
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  • 5BARCIA E,HERRERO-VANRELL R,DIEZ A,et al.Downregulation of endotoxin-induced uveitis by intravitreal injection of polylactic-glycolic acid (PLGA) microspheres loaded with dexamethasone[J].Exp Eye Res,2009,89(2):238-245.
  • 6KAWAKAMI S,HARADA A,SAKANAKA K,et al.In vivo gene transfection via intravitreal injection of cationic liposome/plasmid DNA complexes in rabbits[J].Int J Pharm,2004,278(2):255-262.
  • 7CARMEN C,RUIZ R,CORDERO E,et al.Determination and pharmacokinetic profile of liposomal foscrnet in rabbit ocular tissues after intravitreal administration[J].Exp Eye Res,2009,88(3):528-534.
  • 8CAMELO S,LAJAVARDI L,BOCHOT A,et al.Protective effect of intravitreal injection of vasoactive intestinal peptide(VIP)-loaded liposomes on experimental autoimmune uveoretinitis[J].J Ocul Pharmacol Ther,2009,25(1):9-21.
  • 9LAJAVARDI L,CAMELO S,AGNELY F,et al.New formulation of vasoactive intestinal peptide using liposomes in hyaluronic acid gel for uveitis[J].J Control Release,2009,139(1):22-30.
  • 10Hui YN,Liang HC,Cai YS,et al.Corticosteroid and daunomycin in the prevention of experimental proliferative vitreoretinopathy induced by macrophages[J].Graefe's Arch Clin Ophthalmol,1993,231 (2):109-114.

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