药物流产后阴道出血与子宫刮出物病理学观察分析

Analysis of vaginal bleeding after drug abortion and pathological findings of intra-uterine tissue

目的 探讨药物流产后阴道出血时间与药流后妊娠残留物、血 β HCG的关系。 方法 应用米非司酮配伍米索前列醇时对 4 0 0例早中孕妇女进行药物流产和随访 ,对排出胚胎和绒毛组织后 30d内阴道出血量多、出血时间长、伴血 β HCG下降缓慢的 75例进行清宫术 ,刮出子宫内容物进行病理检查。 结果 变性炎症绒毛 13例 ,滋养细胞残留 30例 ,蜕膜组织 18例 ,全部伴有炎症细胞浸润 ;子宫内膜炎 12例 ,增生期或分泌期子宫内膜 2例。结论 药物流产后阴道出血时间长主要是绒毛、滋养细胞残留 ,一般伴血 β HCG下降缓慢或异常。

Objective To investigate the relationship among vaginal bleeding time,gestational residue and blood β-HCG level after drug abortion.Methods Four hundred women of early or midtrimester pregnancy underwent drug abortion with mifepristone and misoprostol and followed up.Among them 75 cases who had much vaginal bleeding,long time of bleeding and slow drop of blood β-HCG in 30 days after ejecting embryon and villus tissue received uterine curettage.Intra-uterine tissue of curettage were examed pathologically.R...