摘要
目的:探讨复方丹参注射液和甲基强的松龙对大鼠急性脊髓损伤的治疗作用。方法:采用 Allen法将64只 SD 大鼠制成脊髓中度损伤模型,分别给予复方丹参注射液(丹参组)、甲基强的松龙(西药组)、两药联合应用(联合组)及生理盐水(对照组)治疗,观察比较治疗前后动物不同时间的神经功能评分、斜板试验及体感诱发电位。结果:从伤后3周起,治疗组各项指标与对照组比较差异均有显著性(P<0.01),联合组与丹参组及西药组比较差异有显著性(P<0.05)。结论:复方丹参注射液与甲基强的松龙联合应用治疗脊髓损伤具有协同作用。
Objective:To explore the therapeutic effect of Compound Salvia Injection and methylprednisolone in treating rats with acute spinal cord injury.Methods:Sixty-four moderate spinal cord injury model rats,established by Allen method were randomly divided into 4 groups in which they received Compound Salvia Injection (Salvia group),methylprednisolone (western medicine group),com- bined two drugs (combination group) or normal saline (control group),respectively.Tarlov scale,inclined plane test and somatosen- sory...
出处
《中国中西医结合杂志》
CAS
CSCD
北大核心
2003年第S1期165-167,共3页
Chinese Journal of Integrated Traditional and Western Medicine
基金
江苏省中医药局资助项目(No.390-01sz2)
关键词
复方丹参注射液
甲基强的松龙
脊髓损伤
治疗
Compound Salvia Injection
methylprednisolone
spinal cord injury
treatment
