期刊文献+

Survivin基因蛋白在子宫内膜腺癌组织的表达 被引量:5

Expression of Survivin in Adenocarcinoma of the Endometrium
下载PDF
导出
摘要 目的 测定 Survivin在子宫内膜腺癌组织中的表达。 方法 采用 SP免疫组织化学方法 ,对 39例子宫内膜腺癌 ,10例子宫内膜增殖症和 10例增殖期子宫内膜进行 Survivin检测。 结果  30例子宫内膜腺癌 Sur-vivin阳性 (76 .92 % ) ,子宫内膜增殖症和增生期宫内膜均阴性。 结论  Objective\ To detect the expression of survivin in adenocarcinoma of the endometrium.\ Methods\ The expression of survivin in 39 cases of adenocarcinoma of the endometrium, 10 cases of endometrial hyperplasia and 10 cases of proliferative phase of endometrium were detected by immunohistochemical SP method.\ Results\ There were 76 92% positive rate of survivin in adenocarcinoma of endometrium, otherwrise the endometrial hyperplasia and proliferative phase of endometrium were negative.\ Conclusion\ Survivin ...
出处 《福建医科大学学报》 2003年第S1期75-76,共2页 Journal of Fujian Medical University
关键词 子宫内膜肿瘤 抑制蛋白 adenocarcinoma of endometrium survivin
  • 相关文献

参考文献3

二级参考文献16

  • 1Dieffenbach CW 黄培堂等(译).PCR技术实验指南[M].北京:科学出版社,1999.206-217.
  • 2Tanaka K,Clin Cancer Res,2000年,6卷,127页
  • 3Grossman D,Lab Invest,1999年,79卷,1121页
  • 4黄培堂(译),PCR 技术实验指南,1999年,206页
  • 5Lu C D,Cancer Res,1998年,58卷,1808页
  • 6La Casse E C,Oncogene,1998年,17卷,3247页
  • 7Kevin M R,Biochem J,1996年,314卷,7133页
  • 8Wright M E,FEBS Lett,2000年,481卷,13页
  • 9Hirotani M,JBiolChem,1999年,274卷,20415页
  • 10Chao D T,AnnuRevImmunol,1998年,16卷,395页

共引文献144

同被引文献49

  • 1钱铖,刘顺英,孙为豪.幽门螺杆菌感染与胃癌及癌前病变环氧化酶-2表达的研究[J].江苏医药,2004,30(7):546-546. 被引量:6
  • 2陈世耀,汪全红,刘天舒,王吉耀.生存素基因在胃癌组织中的表达及其与胃癌预后关系[J].中华消化杂志,2005,25(5):280-283. 被引量:7
  • 3Yang E,Zha T,Tockel J,et al.Bad,aheterodimeric parmer for Bcl-XL and bcl-2 displaces bax and promotes cell death[J].Cell,1995,80(2):285-291.
  • 4Ambrosini G,Adida C,Altieri DC.A novel anti-apoptosis gene,survivin,expressed in cancer and lymphoma[J].Nature Med,1997,(8):917-921.
  • 5Tamm I,Wang Y,Sausville E,et al.IAP-family protein survivin inhibits caspase activity and apoptosis induced by Fas(CD95),Bax,caspases and anticancer drugs[J].Cander Res,1998,58(23):5315-5320.
  • 6Suzuki A,Ito T,Kawano H,et al.Survivin initiatesptro capase3 p21 complex formationasaresult of interaction with CDK4 to resist Fas-mediated cell death[J].Oncngene,2000,19(10):1346-1353.
  • 7Li F,Ackermann EJ,Bennett CF,et al.Pleiotropic cell division defects and apoptosis induced by interference with survivin function[J].Nat Cell,1999,1(8):461 -466.
  • 8Papapetropoulos A,Fulton D,Mahboubi K,et al.Amgiopioetin-1 inhibits endothelial cell[J].Biol Chem,2000,275 (13):9102-9105.
  • 9Li F,Ambrosini G,Chu EY,et al.Control of apoptosis and mitotic spindle checkpoint by survivin[J].Nature,1998,396(6711):580-584.
  • 10Adida C,Crotty PL,Mograth J,et al.Developmentally regulated expression of the novel cancer antiapoptosis gene survivin in human and monse differentiation[J].Am J Pathol,1998,152(1):43-49.

引证文献5

二级引证文献14

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部