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选择性环鸟苷酸-磷酸二酯酶5抑制药的研究进展 被引量:1

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作者 田平林
出处 《医药导报》 CAS 2003年第S1期50-51,共2页 Herald of Medicine
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参考文献7

  • 1Jun K,Kotomi F.Characterization and effects of methy1-2(4-aminopheny1 )-1, 2-dihydro-1-oxo-7 ( 2-pyridinylmethoxy )-4-( 3, 4, 5trimethozypheny1) -3-isoquinoline carboxylate sulfate(T-1032), a novel potent inhibitor of cGMP-binding cgmp-specific phosphodiesterase (PDE5)[].Biochemical Pharmacology.2000
  • 2David P,Rotella,Sun Z,et al.N-3-substituted imidazoquinazolinones:potent and selective PDE5 inhibitors as potential agents for treatment of erectile dysfunction[].Journal of Medicinal Chemistry.2000
  • 3Turko I V,Ballard S A.Francis SH and corbin JD inhibition of cyclic GMP-binding cyclic GMP-specific phosphodiesterase (Type 5) by sildenafil and related compounds[].Molecular Pharmacology.1999
  • 4Moohi K,Wonbae Chang M S.Preparation of pyrazolopyrimidinones for the treatment of impotence PCT[].Int Appl.2000
  • 5Nicholas K T,Andrew S B,David B,et al.Sildenafil(viagra), a potent and selective inhibitor of type 5 cGMP phosphodiesterase with utility for the treatment of male erectile dysfunction[].Bioorganic and Medicinal Chemistry Letters.1996
  • 6Stief A,Christian G.Phosphodiesterase inhibitors in the treatment of erectile dysfunction[].Drugs of Today.2000
  • 7Nobuhisa W,Yasuhiro K,Yasutaka T,et al.4-Benzylamino-1-chloro-6substituted phthalazines; Synthesis and inhibitory activity toward phosphodiesterase 5[].Journal of Medicinal Chemistry.1998

同被引文献9

  • 1Al-Ghazawi M, Tutunji M, Ahuruz S, Simultaneous determination of sildenafil and N-desmethyl sildenafil in human plasma by high-performance liquid chromatography method using electrochemical de tection with application to a pharmacokinetic study [J]. JPharmBiomedAnal, 2007, 43 (2) : 613 -- 618.
  • 2Pistos C, Papoutsis I, Dona A, et al. Off-line HPLC method combined to LC-MS for the determi nation of sildenafil and its active metabolite in postmortem human blood according to confirmation criteria [J] . Forensic Sci Int, 2008, 178 (2/3) : 192 -- 198.
  • 3Wang Y, Wang J, Cui Y, et al. Liquid chromato graphic-tandem mass spectrometric method for the quantitation of sildenafil in human plasma [J]. J Chromatogr B Analyt Technol Biomed Life Sci, 2005, 828 ( 1/2 ) : 118 -- 121.
  • 4Lewis RJ, Johnson RD, Blank CL. Quantitative determination of sildenafil (Viagra) and its metabolite (UK-103, 320) in fluid and tissue specimens obrained from six aviation fatalities[J]. J Anal Toxicol, 2006, 30 ( 1 ) : 14 -- 20.
  • 5Sheu MT, Wu AB, Yeh GC. Development of a liquid chromatographic method for bioanalytical applications with sildenafil[J].J Chromatogr B Analyt Technol Biomed Life Sci, 2003, 791 (1/2) : 255 -- 262.
  • 6Vos RM, Chahbouni A, Sinjewel A. Quantitative analysis of sildenafil and desmethylsildenafil in human serum by liquid chromatography-mass spectrometry with minimal sample pretreatment [J].J Chromatogr B Analyt Technol Biomed Life Sci, 2008, 876 (2): 283--287.
  • 7Tracqui A, Ludes B. HPLC-MS for the determination of sildenafil citrate (Viagra) in biological fluids. Application to the salivary excretion of sildenafil after oral intake [J] . J Anal Toxicol, 2003, 27 ( 2) :88 -- 94.
  • 8Alkharfy KM. Simple and sensitive LC-ESI-MS method for the quantitation of sildenafil in plasma samples [J].J Sep Sci, 2009, 32 ( 22 ) : 3866- 3870.
  • 9杨士云,袁增平,乔静.全血中西地那非的HPLC分析[J].中国法医学杂志,2009,24(6):392-393. 被引量:3

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