摘要
目的:评价液基细胞学检查(liquid-based pap test,LPT)配合阴道镜检查对子宫颈病变的诊断价值。方法:收集妇科门诊就诊患者11 709例,先后进行LPT检查和阴道镜检查,对细胞学检查或阴道镜检查异常的6223例进行活检。结果:宫颈癌前病变(CIN)的高发年龄为30~40岁,宫颈癌的高发年龄为50~60岁。LPT和阴道镜对对低度鳞状上皮内瘤变(LSIL)、高度鳞状上皮内瘤变(HSIL)、宫颈浸润癌的诊断符合率逐级显著升高;LPT和阴道镜对宫颈病变的诊断敏感性分别为49.02%和80.00%,特异性分别为97.03%和99.08%,差异有显著性。病理诊断中宫颈湿疣者共467例,占所有阳性诊断的54.00%;LPT和阴道镜对单纯宫颈湿疣的漏诊率分别为69.06%和35.91%。结论:LPT诊断宫颈病变敏感性较低,LPT联合阴道镜检查可以提高宫颈病变筛查的准确性,有利于早期诊断宫颈癌及癌前病变。LPT和阴道镜对宫颈湿疣的漏诊率较高,对HPV的检测或将成为宫颈病变的常规筛查手段。
Objective:To assess the value of liquid-based pap test(LPT)and colposcopy in the diagnosis of cervical lesion.Methods:Eleven thousand seven hundred and nine outpatients were given LPT and colposcopy.Cervical biopsies under the guidance of colposcopy were taken in 6223 cases,which were found abnormal by LPT or colposcopy.Results:Cervical intraepithelial neoplasia(CIN)was more likely happened in women aged 30～40 years,while cervical carcinoma was more likely happened in women aged 50～60 years.The diagnosis ac...
出处
《华西医学》
CAS
2008年第5期1099-1100,共2页
West China Medical Journal
关键词
液基细胞学
阴道镜
宫颈病变
liquid-based pap test（LPT）
colposcopy
cervical lesion
