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丙泊酚复合氯胺酮麻醉用于小儿非住院手术的临床观察

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摘要 目的观察丙泊酚复合氯胺酮作用于小儿静脉麻醉的优缺点。方法选择ASAⅠ~Ⅱ级手术患儿40例,男26例,女14例,随机分成两组,每组20例,M-K组为咪唑安定氯胺酮组,P-K组为丙泊酚氯胺酮组。麻醉诱导:肌注氯胺酮4~6 mg/kg,维持:P-K组用丙泊酚1.5 mg/kg、氯胺酮2 mg/kg;M-K组用咪唑安定0.1 mg/kg、氯胺酮2 mg/kg。记录麻醉前和用药后5、10、20、30和60 min ECG、BP、RR、SpO2各值。结果两组在用药后均出现呼吸抑制,M-K组20min后逐渐正常。P-K组10 min后渐正常。M-K组从末次给药算起至小儿完全清醒时间为(110±30)min,术后出现恶心、呕吐、恶梦及异常行为等现象占70%。P-K组手术结束后10~15 min唤醒试验满意,无哭闹、呼叫睁眼,未出现恶心、呕吐、恶梦及异常行为等现象。结论通过本组临床观察,我们认为微泵静注丙泊酚-氯胺酮麻醉效果确切,副作用小,苏醒迅速,可控性强,是小儿非住院手术麻醉的最佳选择。
作者 范红军
出处 《河南外科学杂志》 2008年第5期25-26,共2页 Henan Journal of Surgery
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