亳菊花中黄酮类化合物的分离鉴定

Isolation and Identification of Flavonoids in Chrysanthemum morifolium Ramat.

菊花为菊科植物菊(Chrysanthemum morifolium Ramat.)的干燥头状花序,为了进一步揭示药理活性的物质基础,为该中药的开发利用和质量评价提供依据,安徽亳州亳菊花中的黄酮类化合物进行了系统研究。亳菊经醇提、萃取、硅胶柱层析与纯化得到4个黄酮类化合物。通过理化常数和波谱解析鉴定了其中3个化合物的结构,分别为:芹菜素-7-甲醚(Apigenin-7-methyl ether)(Ⅰ)、芹菜素(Apigenin)(Ⅱ)和木犀草素(Luteolin)(Ⅲ),另外1个化合物的结构尚在鉴定中。上述3个化合物均为首次从该植物中分到的已知化合物。

Four compounds were isolated from the ethyl alcohol extract of the dry-head flower of Chrysanthemum morifolium Ramat.On the basis of physiochemical properties and spectral data,these compounds were identified as Apigenin-7-methyl ether(Ⅰ),Apigenin(Ⅱ),Luteolin(Ⅲ).They were obtained from this plant for the first time.