泌尿生殖道感染支原体培养及药敏的研究

Research on the Antibiotic Resistance of Mycoplasma Infection in Genitourinary Tract

目的对2007年泌尿生殖系感染患者行支原体的检测及药敏分析以指导临床合理使用抗生素。方法应用法国梅里埃公司IST试剂盒作支原体培养鉴定及药敏试验。结果600例患者分离到支原体335株,标本阳性率为55.8%,其中解脲支原体(Uu)阳性率占63.3%,人型支原体(Mh)阳性率占5.1%。Uu+Mh混合型阳性率占31.6%,药敏结果显示,支原体对原始霉素、强力霉素、交沙霉素、四环素敏感性的平均值分别为97.3%、95.2%、92.2%、87.1%,而环丙沙星、氧氟沙星耐药率最高平均值分别为84.7%、68.6%。结论原始霉素、强力霉素、交沙霉素可作为目前泌尿生殖系支原体感染的临床经验性选用的抗生素。但应加强对支原体的耐药性的监测,指导临床合理使用抗生素。

Objective To analyze the antimicrobial susceptibility of Mycoplasma isolates for rational antimicro-bial therapy. Methods BioMerieux IST kit was used for identification and susceptibility testing of the Mycoplasma strains. Results Mycoplasma positive was detected in 335 cases (55.8%) among 600 cases. Of the Mycoplasma detected,Ureaplasma urealyticum(Uu) alone accounted for 63.3%,Mycoplasma huminis (Mh) alone accounted for 5.1%,and Uu+Mh was indentified in 31.6%.The results of antimicrobial susceptibility te...