摘要
目的对比观察佩尔地平与三磷酸腺苷在动脉导管结扎术中控制性降压的临床效能。方法选择先天性心脏病动脉导管未闭行开胸导管结扎术的病人40例,ASAⅠ～Ⅱ级,随机分为为三磷酸腺苷(A)组和佩尔地平(B)组,每组20例。降压时A组缓慢静注ATP0.5～1mg·kg-1,B组缓慢静注佩尔地平3～5μg·kg-1。注药时每1、2、3、4、5、10、15min分别记录SBP、DBP、HR。结果2组降压效果均较好,但B组降压程度及时间均大于A组(P<0.05),A组降压过程中心率减慢较B组明显,2组比较差异有极显著性意义。结论佩尔地平和ATP均适合用于动脉导管结扎手术中的控制性降压,而佩尔地平在降压过程中心率变化较稳定有一定的优点。
Objective To compare clinical efficacy of perdipine and adenosine triphosphate (ATP)in controlled hypotension during ductus arteriosus ligation. Methods A total of 40 patients (ASAⅠ-Ⅱ) with congenital patent ductus arteriosus treated with thoracic duct ligation were enrolled in the study and randomly divided into ATP group (Group A) and perdipine group (Group B), 20 patietns in each group. The patients in Group A were injected intravenously with ATP for 0.5～1mg·kg-1 and those of Group B with perdipine for 3...
出处
《中国血液流变学杂志》
CAS
2008年第2期245-246,262,共3页
Chinese Journal of Hemorheology
关键词
控制性降压
动脉导管未闭
佩尔地平
三磷酸腺苷
controlled hypotension
patent ductus arteriosus
adenosine triphosphate
perdipine
