摘要
目的比较妥塞敏和止血芳酸治疗肺结核咯血的效果和不良反应。方法于2002—2003年采用前瞻性、随机抽样和多中心研究方法,选入并分析轻度和中度咯血患者118例,其中采用妥塞敏60例、止血芳酸58例。2组性别、年龄、病变、咯血严重程度和咯血史以及合并支气管扩张均相似。结果妥塞敏组和止血芳酸组3日咯血治愈率分别为55%和41.4%(P>0.05);7日治愈率分别为95%和81%(P<O.01)。妥塞敏和止血芳酸对初治咯血疗效要优于多次咯血者,无明显不良反应。结论3日妥塞敏效果与止血芳酸相似,而7日妥塞敏则优于止血芳酸。
Objective To compare the efficacy and safety of TXA and PAMBA in the treatment of tuberculosis with hemoptysis.Methods A prospective randomized multicenter study was con- ducted from 2002 to 2003.Tuberculosis patients with mild to moderate hemoptysis were assigned to the TXA group(n=60)and the PAMBA group(n=58).The patients were similar with respect to sex and age distribution,history and severity of hemoptysis,and bronchiectasis.Results The cure rates were 55% for the TXA group and 41.4% for the PAMBA grou...
出处
《中国防痨杂志》
CAS
2008年第2期109-113,共5页
Chinese Journal of Antituberculosis
关键词
结核
肺
咯血
妥塞敏
止血芳酸
Pulmonary tuberculosis
Hemoptysis
Tranexamic acid
Para-aminomethylbenzoic acid
