头颈部恶性淋巴瘤临床分析

A Clinical Analysis on Malignant Lymphoma in Maxilloface and Neck

目的 探讨头颈部ML的诊断方法与治疗措施。方法 4 1例患者采用综合治疗 ,2 7例采用单纯化疗或放疗。结果 6 8例患者 1、3、5年生存率分别为 4 4 .12 %、19.12 %和 13.2 3%,存活患者中以临床I、Ⅱ期者占绝大多数 ,死亡患者中以Ⅲ、Ⅳ期为多。结论 头颈部ML发病率有增长趋势 ,对颈部原因不明的淋巴结肿大应反复活检以明确诊断 ,综合治疗是最为有效的治疗手段 ,临床分期对预后有重要参考价值。

Objective To investigate the diagnosis and treatment of malignant lymphoma (ML) in maxilloface and neck. Methods 41 cases accepted systemic treatment, 27 accepted cases chemotherapy or radiotherapy only. Results The survival rate of 1,3 and 5 years for 68 patients was 44.12%, 19.12% and 13.23% respectively. Among survivals, most were I and II clincal stage, while in those dead patients, most belonged to III and IV stage. Conclusion There is an significant increasing trend for incidence of ML in maxilloface and neck and repeated biopsy should be carried out if mass is unclear in these regions. Chemotherapy combined with radiotherapy and operation is still the effective therapeutic means.The clinical stage classification is important for the prognosis.