急性肺水肿是输液相关性死亡的主要原因

The pathological study of the death induced by transfusion

目的 探讨输液相关性死亡的病理学特点及死亡原因。方法 对1990年～2001年间医疗纠纷尸检档案中28例输液相关性死亡的资料进行分析。结果 输液过程中死亡以中老年男性为主,输液相关死亡多发生在基层医疗单位内科性质科室。死亡多发生在输液4h内,绝大多数患者在临死前有呼吸困难的表现。尸检发现死者大体呈溺死肺样改变,重量增加1～2倍。结论 输液引起死亡的原因以急性肺水肿为主,其次为输液过多致动脉瘤破裂。

Objective To explore the pathological characteristics of the death induced by transfusion . Methods 28 cases of transfusion-related death which were involved in medical tangles were autop-sied by school of forensic medicine from 1990 to 2001. The data were analyzed retrospectively. Results Majority of the patients were male adults. Most died within 4 hours after transfusion. They almost had dyspnea before death.The weight of lung increased 1-2 times than the normal.Conclusion The transfusion-related death is mainly ascribed to acute pulmonary edema while 4 cases was caused by arterial a-neurysm rupture. Strict regulation must be built up to prevent the death induced by transfusion.