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Immunohistochemical Study of HLA-DR Antigen in Endometrial Tis-sue of Patients with Endometriosis 被引量:1

Immunohistochemical Study of HLA-DR Antigen in Endometrial Tissue of Patients with Endometriosis
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摘要 In order to evaluate the expression of HLA DR antigen in glandular cells in eutopic and ectopic endometrium in patients with endometriosis, 19 infertile patients with endometriosis were analyzed immunohistochemically by labelled streptavidin biotin (LSAB) method. Nineteen infertile patients without endometriosis were studied as controls. The results showed that the expression of HLA DR antigen in the glandular cells in both eutopic and ectopic endometrium was increased significantly as compared with that in the controls ( P <0.01). It is likely that aberrant expression of HLA DR antigen in endometriotic tissue is involved in abormal immunogenesis of endometriosis. In order to evaluate the expression of HLA DR antigen in glandular cells in eutopic and ectopic endometrium in patients with endometriosis, 19 infertile patients with endometriosis were analyzed immunohistochemically by labelled streptavidin biotin (LSAB) method. Nineteen infertile patients without endometriosis were studied as controls. The results showed that the expression of HLA DR antigen in the glandular cells in both eutopic and ectopic endometrium was increased significantly as compared with that in the controls ( P <0.01). It is likely that aberrant expression of HLA DR antigen in endometriotic tissue is involved in abormal immunogenesis of endometriosis.
出处 《Journal of Huazhong University of Science and Technology(Medical Sciences)》 SCIE CAS 2002年第1期60-61,共2页 华中科技大学学报(医学英德文版)
关键词 HLA DR antigen IMMUNOHISTOCHEMISTRY ENDOMETRIOSIS HLA DR antigen immunohistochemistry endometriosis
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