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宫颈人乳头状瘤病毒感染的诊断与药物治疗分析 被引量:1

Analysis of diagnosis and drug treatment of human cervical papillomavirus infection.
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摘要 目的 探讨宫颈人乳头状瘤病毒 (HPV)感染的诊断及药物治疗的效果。方法  12 8例宫颈涂片提示HPV感染 ,2 4 0例阴道镜下观察并作宫颈活检及PCR检测结果分析 ,三者均证实HPV感染者 2 4例 ,分组进行疣脱欣和聚甲酚磺醛药物治疗及随访。结果 两组患者临床治愈时间差异无显著性 (P >0 .0 5 )。结论 宫颈细胞学、阴道镜联合宫颈活检及PCR检测对宫颈亚临床型HPV感染的诊断具有重要意义。药物治疗具有无痛苦、无创面出血、感染等优点 ,易于患者接受。 Objective To analyze the diagnosis and drug treatment for human cervical papillormavirus infection. Methods Twenty-four cases of cervical HPV infection were confirmed by cytopathology, colposcopic biopsy and PCR.They were divided into two groups who were treated by two medicinals. Results The time for cure of the disease in the two groups were no statistical difference. Conclusion The diagnosis of subclinical HPV infection by cytopathology, coposcopic biopsy and PCR is great importance. Treatment with these drugs being painless, with no wound haemorrhage or secondary infection, adn are well tolerated by the patients.
出处 《上海医学》 CAS CSCD 北大核心 2002年第z1期56-57,共2页 Shanghai Medical Journal
关键词 人乳头状瘤病毒 宫颈 诊断 治疗 Human papillormavirus, Cervix Diagnosis, Treatment
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  • 1[3]Ferrera A, Velema JP, Figueroa M, et al. Human papillomavirus infection, cervical dysplasia and invasive cervical cancer in Honduras:a case-control study. IntJCancer, 1999, 82:799-803.
  • 2[4]Serra H, Pista A, Figueiredo P, et al . Cervix uteri lesions and human papiloma virus infection (HPV): detection and characterization of DNA/HPV using PCR. Acta Med Port, 2000,13: 181-192.
  • 3[5]Hording U,Rygaard C,Ruge S,et al.Cervical koilocytosis and high risk HPV types: the benefit of laser vaporization. Eur J Ob-stet Gynecol Reprod Biol, 1993,51:125-130.
  • 4[6]Holmes MM, Weaver SH, Vermillion ST. A randomized, doubleblind, placebo-controlled trial of 5-fluorouracil for the treatment of cervicovaginal human papillomavirus. Infect Dis Obstet Gynecol,1999,7:186-189.

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