海马生髓丸对S_(180)荷瘤鼠、SKOV_3卵巢癌模型鼠抑瘤机理的实验研究

The Mechanism Study on Hai-Ma-Sheng-Sui Pill Resistiug the Tumor on S_(180) and SKOV_3 Mice

以S180荷瘤鼠、SKOV3卵巢癌模型鼠为研究对象,进行海马生髓丸抗肿瘤的实验研究。通过对移植瘤的抑瘤率、光、电镜技术及细胞凋亡调控基因P53、BcL-2等免疫组化的研究,表明海马生髓丸具有一定的抗肿瘤作用,可以抑制S180荷瘤鼠的肿瘤生长,明显增强SKOV3卵巢癌模型鼠DDP的杀伤肿瘤作用,对肿瘤细胞的凋亡具有明显促进作用。

Object:To study the antitumor function on Hai-Ma-Sheng-Shui Pill.Method:The anti-tumor action was observed through the anti-tumor ratio,P 53 gene and bc1-2gene.Result:The hai-Ma-Sheng-Shui Pill can resist the growth of the S 180 and SKOV 3 tumor,and induce the tumor cell apoptosis.