小剂量米索前列醇用于足月妊娠引产的疗效观察

The Effect of Lower Dosage Misoprostol on Inducing Term Labor

目的 探讨小剂量米索前列醇用于足月妊娠引产的有效性和安全性。方法 10 0例有引产指征的足月孕妇随机分为两组 ,A组 5 0例使用米索前列醇 ,首剂 5 0ug ,以后根据宫缩情况间隔 2～ 6h追加一次剂量 ;B组5 0例静滴催产素引产作为对照。结果 两组引产成功率分另 88% ,76 % (P >0 0 5 )。A组从开始用药至临产的平均时间明显短于B组 (P <0 0 5 )。两组剖宫产率、产后 2h出血量及生儿窒息的发生率间差异无显著性。结论 小剂量米索前列醇用于足月孕妇引产是一种安全、有效、方便的办法 ,且效果优于催产素。

Objective To determine the efficacy and safety of lower dosage misoprostol for inducing term labor.Methods 100 women at term with indications of labor induction were divited into two groups,50 women(group A) received misprostol 50 ug at the beginning,then a second dosage was given according the situation of the contractions of uterus every 2 to 6 hours;50 women(group B) received intravenous oxytocin as controls.Results The success rate of labor induction was 88% in group A and 76% in grouop B(P>0 0...