摘要
为观察喂养缺锌饲料对孕鼠生长发育及其肝脏、胎盘中谷胱甘肽过氧化物酶(GSH-PX)及过氧化氢酶(CAT)活性的影响。将16只受孕Wistar鼠随机分为缺锌组(ZD组)、加锌组(ZS组)和正常对照组(ZC组),分别喂饲缺锌饲料、加锌饲料和基础饲料,记录每只孕鼠每日体重变化。于妊娠21日将孕鼠处死,取其肝脏、胎盘作GSH-PX和CAT活性测定。结果为ZD组孕鼠体重未见增加,SC组和ZS组孕鼠体重增加明显;与ZC组和ZS组相比,ZD组孕鼠肝脏和胎盘中GSH-PX活性显著降低(P<0.05),孕鼠肝脏和胎盘中CAT活性显著升高(P<0.05)。故认为缺锌可影响孕鼠肝脏、胎盘中谷胱甘肽过氧化物酶及过氧化氢酶活性,并影响其生长发育。
To investigate the effects of Zn deficiency on the growth and the activities of GSH-PX,CAT ofthe livers and the placentas in pregnant rats. Sixteen pregnant Wistar rats were randomly divided into Zndeficiency group, pair-fed group and control group, then were fed on corresponding diets. The changes of bodyweight were measured every day. The pregnant rats were killed on the 21st day of their pregnancies. Theactivities of GSH-PX, CAT in the placentas and the livers were measured. The body weight of Zn deficie...
出处
《山东医药》
CAS
北大核心
2002年第36期1-3,共1页
Shandong Medical Journal
关键词
缺锌
孕鼠
生长发育
肝脏
胎盘
GSH-PX
CAT
Zinc deficiency
Pregnant rats
Growth and development
Liver Placenta
GSH-PX
CAT
