期刊文献+

肝移植术后早期细菌感染流行病学分析 被引量:3

Epidemic analysis of bacterial infection after liver transplantations
下载PDF
导出
摘要 目的探讨肝移植术后细菌感染的流行病学特征。方法回顾性分析该院2003年3月~2006年12月53例肝移植术后细菌感染的特征。结果53例肝移植受者36例发生感染,感染率67.9%,感染组死亡相对危险度是对照组2.14倍,感染最常见于肺部,时间为术后2~42d,常见致病菌为大肠埃希氏菌。送检795份标本,阳性386份,阳性率50.9%。最常见感染标本为痰液,占31.9%。两个或以上部位感染32例,占88.9%。革兰阴性菌大部分对氨基糖苷类、β-内酰胺酶抑制剂复合制剂、碳青霉烯类敏感,对喹诺酮类、三代、四代头孢菌素耐药;革兰阳性菌对青霉素类、喹诺酮类和碳青霉烯类耐药,仅对万古霉素敏感。结论肝移植术后感染率和病死率高,感染最常见于肺部,致病菌为耐药菌,对多种常用抗生素耐药。 Objective To explore the epidemical characteristics of bacterial infections after liver transplantations.MethodsThe data of 53 liver recipients from 2003.3~2006.12 were retrospectively analyzed, including the morbidity and mortality, the death odds ratio, the common infectious sites and bacterial strains, the bacterial sample distributions and antibiotic sensitivity tests.ResultsAmong 53 recipients, 36 developed infections(account for 67.9%), 8 died(15.1%).The death odds ratio of the infectious was 2.14 tim...
机构地区 解放军第
出处 《中国现代医学杂志》 CAS CSCD 北大核心 2008年第20期2998-3001,共4页 China Journal of Modern Medicine
关键词 肝移植 细菌感染 流行病学 特征 liver transplantation bacterial infection epidemical characteristic
  • 相关文献

参考文献5

二级参考文献25

  • 1潘澄,Ashok Jain,John J.Fung.肝移植术后晚期合并多器官功能衰竭主要死因分析[J].中国危重病急救医学,2004,16(9):547-551. 被引量:16
  • 2王鹏远,杨尹默,吴问汉,田孝东,刘玉村,万远廉,黄莛庭.肝移植术后感染细菌学和耐药性及相关因素分析[J].中华肝胆外科杂志,2004,10(12):808-810. 被引量:7
  • 3穆红,张坚磊,陈锦艳,王世瑜.肝移植术后胆道感染患者的革兰氏阴性细菌耐药性监测[J].天津医科大学学报,2005,11(1):99-101. 被引量:3
  • 4沈中阳,刘懿禾,于立新,王峪,刘蕾.1510例成人原位肝移植患者围手术期的管理[J].中国危重病急救医学,2005,17(10):589-591. 被引量:26
  • 5Sigh N.Infectious diseases in the liver transplant recipient[J].Semin Gastrointest,1998,9(3):136.
  • 6Losada I,Cuervas-Mons V,Millan I,et al.Early infection in liver transplant recipients:incidence,severity,risk factors and antibiotic sensitivity of bacterial isolates[J].Enferm infeccn Microbiol Clin,2002,20:422.
  • 7Hollenbeak CS,Alfrey EJ,Souba WW.The effect of surgical site Infections on outcomes and resource and utilization afte liver transplantation[J].Surgery,2001,130(2):388-395.
  • 8Sigh N,Wagener MM,Obman A,et al.Bacteremias in liver transplant recipients:shift toward gram-negative bacteria as predominant pathogens[J].Liver Transplaspl.2004,10(7):844-849.
  • 9Govea EF,Branco RC,Montero RC,et al.Outcome of infections caused by multiple drug-resistant bacteria in liver transplant recipients[J].Transplant Proc,2004,36(4):958-960.
  • 10Singh N. Infectious diseases in the liver transplant recipient[J]. Semin Gastrointest Dis, 1998, 9:136-146.

共引文献63

同被引文献16

引证文献3

二级引证文献6

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部