摘要
目的探讨肝移植术后细菌感染的流行病学特征。方法回顾性分析该院2003年3月~2006年12月53例肝移植术后细菌感染的特征。结果53例肝移植受者36例发生感染,感染率67.9%,感染组死亡相对危险度是对照组2.14倍,感染最常见于肺部,时间为术后2~42d,常见致病菌为大肠埃希氏菌。送检795份标本,阳性386份,阳性率50.9%。最常见感染标本为痰液,占31.9%。两个或以上部位感染32例,占88.9%。革兰阴性菌大部分对氨基糖苷类、β-内酰胺酶抑制剂复合制剂、碳青霉烯类敏感,对喹诺酮类、三代、四代头孢菌素耐药;革兰阳性菌对青霉素类、喹诺酮类和碳青霉烯类耐药,仅对万古霉素敏感。结论肝移植术后感染率和病死率高,感染最常见于肺部,致病菌为耐药菌,对多种常用抗生素耐药。
Objective To explore the epidemical characteristics of bacterial infections after liver transplantations.MethodsThe data of 53 liver recipients from 2003.3~2006.12 were retrospectively analyzed, including the morbidity and mortality, the death odds ratio, the common infectious sites and bacterial strains, the bacterial sample distributions and antibiotic sensitivity tests.ResultsAmong 53 recipients, 36 developed infections(account for 67.9%), 8 died(15.1%).The death odds ratio of the infectious was 2.14 tim...
出处
《中国现代医学杂志》
CAS
CSCD
北大核心
2008年第20期2998-3001,共4页
China Journal of Modern Medicine
关键词
肝移植
细菌感染
流行病学
特征
liver transplantation
bacterial infection
epidemical characteristic