高血压患者血压昼夜节律异常与心率变异性关系

Relationship between Changes of BP Rhythmicity and Heart Rate Variability in Patients with Essential Hypertension

目的 探讨高血压患者血压昼夜节律异常与心率变异性关系。 方法 应用动态血压监测仪和动态心电图分析仪记录患者 2 4h的血压和心率变化 ,并设年龄相似的健康者作对照组。高血压患者 10 6例 ,分 3级 (1级 38例 ,2级 43例 ,3级 2 5例 ) ;对照组 30例。高血压患者进行血压昼夜规律分析 ,高血压患者和对照组行心率变异性 (HRV) (时域指标和频域指标 )分析。 结果 1级高血压患者血压昼夜规律全部正常 ,2级 6例正常、37例消失 ,3级全部消失 ;3级高血压患者血压昼夜变异比 2级小 (P<0 .0 5 ) ;血压昼夜规律异常者 HRV降低 ,3级高血压患者 HRV显著低于 2级 (P<0 .0 1)。 结论 高血压患者血压昼夜规律异常与心率变异性呈正相关 ,与靶器官损害呈正相关。

Objective\ To investigate the relationship between changes of BP rhythmicity and heart rate variability(HRV) in patients with essential hypertension(EH).\ Methods \ To use ambulatory blood pressure monitoring(ABPM) and Holter monitor, variability of heart rate and blood pressure in 24 hours were compared with the controlled group.\ The hypertensive patients(n=106) [stage one([WTBX]n=38), stage two(n=43), stage three(n=25)] and normal BP( and normal BP(n=30) were observed.\ Changes of BP rhythmicity was inve...