地尔硫缓释片与硝苯地平治疗不稳定性心绞痛对比观察

A comparison observation of diltiazem and nifedipine in treatment of unstable angina pecoris

目的 :比较地尔硫缓释片与硝苯地平治疗不稳定性心绞痛 (UAP)的疗效与不良反应。方法 :61例UAP病人 ,男性 4 2例 ,女性 19例 ,年龄(5 1.0±s 2 .6)a (4 5～ 66a)。分为 2组 ,地尔硫组 31例 ,口服地尔硫缓释片 180mg ,bid ;硝苯地平组 30例 ,口服硝苯地平 10mg ,tid ;疗程均为 30d。结果 :地尔硫组和硝苯地平组治疗前后临床疗效总有效率分别为 94 %和 77% (P <0 .0 5 ) ;心电图改善有效率分别为 90 %和 5 7% (P <0 .0 5 ) ;不良反应比较差异无显著意义 (P >0 .0 5 )。结论 :地尔硫缓释片治疗UAP ,不但疗效突出 ,而且不良反应少 。

AIM:To compare the therapy effects and adverse reactions between diltiazem and nifedipine in treatment of unstable angina pectoris (UAP). METHODS: A total of 61 UAP patients [M 42, F 19; age 51.0 a± s 2.6 a (45-66 a)] were randomly divided into diltiazem group ( n =31) and nifedipine group ( n =30). Thirty one patients received diltiazem 180 mg, po , bid in diltiazem group. Thirty patients received nifedipine 10 mg, po , tid in nifedipine group. RESULTS: The differences of therapy effect bet...