西米替丁预防急重症脑血管病并发应激性溃疡出血的研究

Investigations on the Therapeutic Effect of Cimetidine in Preventing Acute and Serious Cerebrovascular Disease Comeplicated by Bleeding Stress Ulcer.

目的 观察在急重症脑血管病中使用H2 受体拮抗剂西米替丁对应激性溃疡发生的预防作用。方法 :将12 2例急重症脑血管病人随机分为常规治疗的对照组和入院时即加西米替丁治疗而其它治疗原则相同的治疗组。比较急性期应激性溃疡出血的发生率 ,治疗组的发生率明显低于对照组 (P <0 .0 1)。

Objective: To observe preventive effect of Cimetidine on bleeding stress ulcer in acute and serious cerebrovascular disease.Methods: 122 patients acute and serious cerebrovascular disease were randomly divided into two groups. the first group of 67 cases were treated with common therapy while the second group of 55 cases with Cimetidine on the base of the common methods. Results: Compared with the second group the happening rate of the first group was very signifcantly increased by statistics. Cimetidine can eflective prevent the happening of bleeding stress ulcer in acute cerebrovascular disease.