氯马斯汀乳膏的制备和质量控制

Preparation and quality control of clemastine fumarate emulsion

目的 :研制氯马斯汀乳膏 ,并研究其质量标准。方法 :以o/w法制备乳膏 ,采用分光光度法测定含量。测定波长为 4 0 6nm。结果 :该乳膏剂制备工艺简单、质量控制方法可行。结论 :氯马斯汀乳膏不仅适用于医院配制 ,而且适用于工业化生产。

OBJACTIVE:To study the prescription,preparation and quality control of clemastine fumarate emulsion.METHODS:The emulsion was prepared by o/w method.Clemastine fumarate was determined by spectrometry method at wavelength of 406nm.RESULTS:The process was simple and practicable,the quality control was reliable.CONCLUSION:The emulsion is suitable not only for small amount of preparation in hospital but also for large batch of production in pharmaceutical industry.