立体定向功能性神经外科不可见靶点的坐标计算方法软件

Software for Computing the Coordinates of the Empirical Targets in Stereotactic Functional Neurosurgery

目的 推导并验证立体定向功能性神经外科不可见靶点坐标计算的方法 ,并将其软件化。方法 采用解析几何学原理 ,推导出靶点与AC -PC线中点之间在前后、上下、左右三个方向的垂直距离值与其在立体定位架中的坐标值之间的换算关系 ,并实现软件化。采用模拟头颅、模拟靶点、Leksell定位架固定、CT扫描定位 ,以及伽玛刀治疗计划系统验证的方法 ,判定换算结果的准确性。结果 换算准确 ,而且可纠正由于头颅在定位架中旋转、倾斜所导致的误差。结论 在测得AC、PC点坐标值和AC -PC线下方大脑正中矢状面上任意一点的坐标值后 ,靶点与AC -PC线中点之间在前后、上下、左右三个方向的垂直距离值与其在立体定位架中的实际坐标值之间是可以互相换算的。此计算方法的软件实用简便。

Objective A software for computing the coordinates of the empirical targets in stereotactic functional neurosurgery was designed and tested.Methods The formula of the conversion relationship between the coordinates of the targets and the distances of the targets anterioposterior to, lateral to and superoinferior to the midpoint of the intercommissural line were deduced. After fixing the Leksell stereotactic frame to a skull model with targets, performing the CT scan and stereotactic localization, then the accuracy of the conversion was tested with TPS of OUR rotating gamma knife.Results The conversion was very accurate and independent of the position of the skull within the stereotactic frame.Conclusion If the coordinates of the AC, the PC and another point in the midline of cerebrum are known, the coordinates of the target and the distances of the target anteroposterior to, lateral to and superoinferior to the midpoint of the intercommissural line will be convertible precisely and conveniently from each other. The software for the converting is practical, convenient and accurate.