不同负荷的运动训练对大鼠T淋巴细胞亚群的影响

Effects of exercise training with different loads on the T-lymphocyte subsets in rats

为了研究运动训练对机体Ｔ淋巴细胞亚群的影响，对大鼠进行为期８周的不同负荷运动训练，测定外周血液中ＣＤ３＋、ＣＤ４＋和ＣＤ８＋Ｔ淋巴细胞的数量。实验结果：运动训练后，ＣＤ３＋Ｔ淋巴细胞在各组之间无显著性差异；１ｈ训练组中，ＣＤ４＋Ｔ淋巴细胞显著高于对照组，ＣＤ８＋Ｔ淋巴细胞与对照组相比虽有下降，但无显普性差异，从而使ＣＤ４＋／ＣＤ８＋显著高于对照组。在力竭性训练组中，ＣＤ４＋细胞显著低于１ｈ训练组，而与对照组相比有下降趋势，但无显普性差异；而ＣＤ８＋细胞显著高于１ｈ训练组和对照组，从而使ＣＤ４＋／ＣＤ８＋显著低于１ｈ训练组和对照组。结果表明，适当的运动训练可以提高机体的免疫功能，而长期力竭性运动训练可导致机体免疫功能的抑制。

In order to explore the effects of exercise training on the immunity, the T-lymphocyte subsets in periph- eral blood were measured after exercise training with different loads for 8 weeks. The results: After exercise train- ing, CD3+ T-lymphocytes were no significance among the three groups. In 1 h training group, CD4+ cells were higher than those in control group significantly. Compared with control group, CD8+ cells had a decrease tenden- cy, but there was no significant difference. The ratio of CD4+ and CD8+ was higher than that on control group significantly. In exhaustive training group, CD4+ cells were lower than those in 1 h training group significantly. Compared with control group, it had a decrease tendency, but there was no significant difference. CD8+ cells were higher than those in control group and in 1 h training group. The ratio of CD4+ and CD8+ was lower than that in 1 hr training group and in control group significantly. The results suggested that mederate exercise training improve the immune function and exhaustive training might cause the immunosuppression.