痰培养分离鉴定1209株念珠菌及药敏结果分析

Sputum Culture Isolation And Drug Resistant Analysis of 1209 Strain of Candidasp

目的了解我院近三年来念球菌检出和耐药情况,寻找规律,分析原因,指导临床诊治.方法对临床合格痰标本用念珠菌显色培养基培养,菌种鉴定和体外药敏实验采用ATB鉴定系统.结果1209株真菌中,以白色念珠菌为主(64.43%),其次是光滑念珠菌(25.39%).2005年耐药性与2006年2007年比较差异有高度显著性意义(p<0.01)且出现多耐药情况.结论念珠菌感梁仍居高位,且多耐药菌株有上升趋势,此种现象的出现推测我院对肺念球菌感染的诊治有过诊过治嫌疑.

Objective To investigate the candida infection and their resistant to antifungal agents in our hospital during the recent three years,explore regularity,analyse cause,and guide clinical diagnosis and treatment.Methods The sputum specimens were cultivated by candida color medium,ATB identification system was be used to do typing and drug sensitivity test of Candida.Results Among 1209 strain candida,the isolation rate of C.albicans was the first(64.43%),the isolation rate of Candida Glabrata was the second(25.39%). Obvious differences between 2005 and 2006 were observed in resistance(P<0.01).Differences between 2005 and 2007 were similar,and multidrug resistant strains were appearing.Conclusion The main pulmonary fungi are monilia,and multidrug resistant strains have an increasing tendency.This shows that we are excessive when we diagnose and treat pulmonary monilia infection in our hospital.