古菌与牙周病的关系

Relations between archaea and periodontal disease

三域分类系统将古菌区别于真核生物和细菌。古菌可生存于极端的生态环境中,如高温、高盐度、高低酸碱度、低氧等环境,也可在普通环境下生长。古菌的细胞结构和分子代谢以及基因转录既不同于原核细胞也不同于真核细胞。用16SrRNA序列研究检测的方法可以检测出人体菌群中无法培养的古菌。牙周病患者口腔中检测出的产甲烷类古菌能加剧牙周组织的破坏,但至今尚未发现致病性的古菌。下面就古菌与牙周病关系的研究进展作一综述。

Archaea which are microorganisms that are distinct from bacteria and eukaryotes, could not only survive under extreme conditions, such as high temperature, high/low pH values, high salinity and anoxic environments, but also exist in normal environments. Genetic information processing machinery and cellular metabolism in archaea show unique characteristics. Archaea can be detected in human body plaque by using not-yet-cultivate independent molecular methods. Methanogenic archaea, which is inspected from peri...