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生物法合成5-氨基乙酰丙酸的研究进展 被引量：3

Recent advances in biosynthesis of 5-aminolevulinic acid
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摘要 对国内外生物法合成5-氨基乙酰丙酸(ALA)的进展进行综述,重点比较了诱变育种法和代谢工程技术在ALA生物合成研究中的应用,揭示了新兴的代谢工程技术在ALA的生产开发中极具应用前景,为生物法合成ALA的进一步发展指明了方向,有利于促进ALA生物合成的产业化。 The research progress in the biosynthesis of 5-aminolevulinic acid(ALA) at home and abroad is reviewed.And the application of induced mutation breeding method and metabolic engineering technology in ALA biotechnological production was discussed in detail.Further study on ALA production can be expected to lead to high productivity of ALA via regulation of metabolic pathway in mircoorganisms.
作者 傅维琦 林建平 岑沛霖
机构地区 浙江大学化学工程与生物工程学系
出处 《现代化工》 CAS CSCD 北大核心 2008年第S2期190-193,共4页 Modern Chemical Industry
基金 国家自然科学基金资助项目(20306026) "973"资助项目(2007CB707805)
关键词 5-氨基乙酰丙酸 生物合成 诱变育种 代谢工程 5-aminolevulinic acid biosynthesis induced mutation breeding metabolic engineering
分类号 TQ226 [化学工程—有机化工]
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参考文献5

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共引文献2

同被引文献35

  • 1宋士清,郭世荣.5-氨基乙酰丙酸的生理作用及其在农业生产中的应用(综述)[J].河北科技师范学院学报,2004,18(2):54-57. 被引量：27
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  • 3康琅,程云,汪良驹.5-氨基乙酰丙酸对秋冬季大棚西瓜叶片光合作用及抗氧化酶活性的影响[J].西北植物学报,2006,26(11):2297-2301. 被引量：58
  • 4何晓梅,周静,程郢,范军.表达酿酒酵母ALAS的重组大肠杆菌胞外5-氨基乙酰丙酸的产量和纯化[J].生物工程学报,2007,23(3):520-524. 被引量：4
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现代化工
2008年 第S2期

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