实时三维超声心动图评价左室整体收缩和舒张功能的研究

Assessment of left ventricular global systolic and diastolic function using real-time three-dimensional echocardiography

目的探讨实时三维超声心动图(RT3DE)评价左室收缩和舒张功能的临床应用价值。方法研究对象分为3组,A组28例健康志愿者,B组24例高血压病患者,C组22例扩张性心肌病的患者。对所有研究对象进行经胸二维和实时三维超声心动图检查,采集组织多普勒图像和全容积三维图像,应用Qlab3DQ软件对三维数据库进行分析,得到左室舒张末容积(EDV)、收缩末容积(ESV)和射血分数(EF),根据三维数据库计算出峰值射血率(PER)、舒张早期峰值充盈率(PFR)、PER/EDV、PFR/EDV。应用QlabSQ软件分析TDI图像,得到等容收缩时间(ICT)、等容舒张时间(IRT)、射血时间(ET)并计算TEI指数。结果B、C组左室容积EDV、ESV均显著大于对A组(均P<0.05),PFR/EDV显著小于A组,IRT显著延长(P<0.05),ET显著缩短,Tei指数显著大于A组(P<0.05),C组EF、PER/EDV、均显著小于A组(均P<0.05),ICT显著延长(均P<0.05)。相关性分析显示PER/EDV与EF、ICT均有较好的相关性(r=0.893,-0.618,均P<0.05),PFR/EDV与IRT有较好的相关性(r=-0.450,P<0.05)。PER/EDV与PFR/EDV之间也有很好的相关性(r=0.839,P<0.05)。结论实时三维超声心动图可客观的评价左室收缩和舒张功能,PER/EDV、PFR/EDV可作为定量评价左室收缩功能和舒张功能的有效指标。

Objective To assess left ventricular global systolic and diastolic function using real-time three-dimensional echocardiography(RT3DE).Methods Subjects were divided into three groups.Group A consisted of twenty-eight normal subject,group B included twenty-four patients with hypertensive(HTN),group C consisted of twenty-two patients having dilated cordiomyopathy(DCM).Participants were selected undergoing full volume real-time three-dimensional echocardiography.The global and 17-segmental volume-time curves we...