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瘦素及其受体与肺癌关系的研究进展 被引量：2

Advance in the study of the Leptin and its receptors ob-R effect on lung cancer
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摘要 瘦素是肥胖基因(ob基因)表达的多肽产物,最初基于对肥胖的研究认为瘦素与其受体(ob-R)结合,起到调节体内脂肪储量和维持能量平衡的作用。近年来研究发现瘦素受体广泛存在于体内各组织器官。
作者 曲晓翰 韩立波
机构地区 中国医科大学附属第一医院胸外科
出处 《中国肺癌杂志》 CAS 2008年第6期821-823,共3页 Chinese Journal of Lung Cancer
关键词 肺癌 肺肿瘤 瘦素 受体
分类号 R734.2 [医药卫生—肿瘤]
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  • 1葛可佑,翟风英,闽怀成,程列,王青,贾凤梅.九十年代中国人群的膳食与营养状况[J].营养学报,1995,17(2):123-134. 被引量：135
  • 2Shoji T, nishizawa Y, Emoto M, et al. Renal funtion and insulin resistance as determinants of plasma leptin levels in patients with NIDDM.Diabetes, 1997,46:335-341.
  • 3Kristenson K, Pedersen SB, Langdahl BL, et al. Regulation of leptin by thyroid hormone in humans:studies in vivo and in vitro. Metabolism,1999,48 : 1603-1607.
  • 4Chu NF, Spiegelman D, Hotamisligil GS, et al. Plasma insulin, leptin,and soluble TNF receptors levels in relation to obesity-related atherogenic and thrombogenic cardiovascular disease risk factors among men.Atherosolerosis ,2001,157:495-503.
  • 5Sato T,Meguid MM,Miyata G,et al. Does leptin really influence cancer anorexia? Nutrition ,2002,18:82-83.
  • 6Mantovani G, Maccio A, Madeddu C, et al. Serum values of proinflammatory cytokines are inversely correlated with serum leptin levels in patients with advanced stage cancer at different sites. J Mol Med,2001,79:406-414.
  • 7Zhang Y, Procenca R, Maffei, et al. Positional cloning of the mouse ob gene and its human homoligue. Nature, 1994,372:425-432.
  • 8De Vita F, Orditura M, Auriemma A, et al. Serum concentrations of proinflammatory cytokines in advanced non small cell lung cancer patients. J Exp Clin Cancer Res,1998 ,17 :413-417.
  • 9Zumbacnech MS, Boehme MWJ, Wahl P, et al. Tumor necrosis factor increase serum leptin levels in humans. J clin Endecrinol metab, 1997,82:4080-4082.
  • 10方圻,王钟林,宁田海,邵耕,陈在嘉,陆宗良,李健斋,林传骧,周北凡,诸骏仁,诸永康,陶萍,陶寿淇,龚兰生,顾复生,游凯,戴玉华.血脂异常防治建议[J].中华心血管病杂志,1997,25(3):169-175. 被引量：3067

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  • 1Terzidis A, Sergentanis TN, Antonopoulos G, et al. Elevated serum lep- tin levels:a risk factor for non-small-cell lung cancer? [ J]. Oncolo- gy ,2009,76( 1 ) : 19-25.
  • 2Ntikoudi E,Kiagia M,Boura P,et al. Hormones of adipose tissue and their biologic role in lung cancer[J]. Cancer Treat Rev,2014,40( 1 ) :22-30.
  • 3Kerenidi T, Lada M, Tsaroucha A, et al. Clinical significance of serum adipokines levels in lung cancer[ J ]. Med Onco1,2013,30 (2) :507.
  • 4Ribeiro R, Araujo AP, Coelho A, et al. A functional polymorphism in the promoter region of leptin gene increases susceptibility for non- small cell lung cancer [ J ]. Eur J Cancer, 2006,42 ( 8 ) : 1188-1193.
  • 5Unsal M, Kara N, Karakus N, et al. Effects of leptin and leptin receptor gene polymorphisms on lung cancer[ J]. Tumour Biol,2014,35 (10) : 10231-10236.
  • 6Le Stunff C, Le Bihan C, Schork N J, et al. A common promoter variant of the leptin gene is associated with changes in the relationship be- tween serum leptin and fat mass in obese girls[ J]. Diabetes,2000,49 (12) :2196-2200.
  • 7Hoffstedt J, Eriksson P, Mottagni-Tabar S, et al. A polymorphism in the leptin promoter region ( -2 548 G/A ) influences gene expression and adipose tissue secretion of leptin [ J ]. Horm Metab Res, 2002,34 (7) :355-359.
  • 8Ribeiro R, Vasconcelos A, Costa S, et al. Overexpressing leptin genetic polymorphism ( -2 548 G/A ) is associated with susceptibility to prostate cancer and risk of advanced disease [ J ]. Prostate, 2004,59 (3) :268-274.
  • 9贾淑云,王敏.胃癌恶病质患者血清瘦素水平的变化[J].宁夏医科大学学报,2009,31(4):497-499. 被引量：1
  • 10余日臻,许静.MicroRNA与肌肉萎缩[J].第二军医大学学报,2015,36(12):1339-1343. 被引量：2

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中国肺癌杂志
2008年 第6期

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