摘要
目的分析神经梅毒的临床特征,做到早期诊断和治疗。方法回顾性分析经实验室检查确诊的6例神经梅毒患者的有关临床资料。结果6例患者中,间质型梅毒3例,实质型梅毒3例,其中1例为脊髓痨,2例为麻痹性痴呆。6例患者的血、脑脊液梅毒抗体均为阳性,脑脊液蛋白含量增高或正常,细胞数增多,以单核细胞为主。神经梅毒的磁共振成像检查表现复杂多样,无特异性;间质型梅毒的影像表现为脑梗死、软脑膜增强等;麻痹性痴呆表现为脑萎缩、双侧颞叶及海马区异常信号。青霉素治疗能明显改善临床症状及预后。结论神经梅毒的临床表现多样,易误诊,临床表现和血清、脑脊液梅毒抗体阳性是确诊的依据。
Objective To analyze the clinical features of neurosyphilis, so as to help the early diagnosis and treatment. Methods The clinical data of 6 patients with confirmed neurosyphilis were retrospectively analyzed. Results The 6 cases included 3 interstitial neurosyphilis and 3 substantial neurosyphilis, with 1 having tabes dorsalis and 2 having general paralysis of insane (GPI). Patients were all positive of syphilis antibody reaction in serum and cerebrospinal fluid (CSF); CSF protein content was increased or ...
出处
《上海医学》
CAS
CSCD
北大核心
2008年第10期718-720,共3页
Shanghai Medical Journal
关键词
神经梅毒
临床表现
诊断
Neurosyphilis
Clinical manifestation
Diagnosis
