摘要
目的探讨贫血对急性心肌梗死(AMI)患者住院期预后的影响。方法2003年1月—2005年12月间资料完整的251例AMI患者,依入院时(6h内)红细胞比积(Hct)水平分为3组:A组,Hct≤0.33(33例);B组,0.33<Hct≤0.39(114例);C组,0.39<Hct≤0.55(104例)。比较各组的病死率和主要心脏不良事件(MACE,包括死亡、心力衰竭、梗死后心绞痛及再梗死)发生率。结果住院期死亡39例(15.5%),发生MACE119例(47.4%)。死亡患者的Hct平均为0.34±0.06,显著低于存活患者的0.38±0.05(P<0.01);发生MACE患者的Hct平均为0.36±0.06,显著低于未发生MACE者的0.39±0.06(P<0.01)。A、B和C组的病死率分别为36.3%、19.3%和4.8%,MACE发生率分别为78.9%、56.2%和27.9%,3组间病死率和MACE发生率的差异均有统计学意义(P值均<0.05)。多因素回归分析显示,Hct水平是决定AMI患者住院期预后的独立因素(P<0.05)。结论贫血是影响AMI患者住院期死亡和发生MACE的重要危险因素之一,纠正严重贫血可能对改善其预后有益。
Objective To evaluate the effect of anemia on in-hospital outcomes of patients with acute myocardial infarction (AMI).Methods The clinical and in-hospital outcome data of 251 consecutive AMI patients were collected from January 2003 to December 2005. These patients were grouped according to plasma haematocrit level ( Hct): Group A included 33 patients with moderate/severe anemia (Hct≤0.33); Group B had 114 patients with mild anemia (0.33<Hct≤0.39); and Group C had 104 patients with normal Hct (0.39<Hc...
出处
《上海医学》
CAS
CSCD
北大核心
2008年第10期687-689,共3页
Shanghai Medical Journal
关键词
急性心肌梗死
贫血
预后
Acute myocardial infarction
Anemia
Prognosis
